By Edward F. Plow PHD, Peter Kelly MD (auth.), Arman T. Askari, A. Michael Lincoff (eds.)
Substantial morbidity and mortality is still linked to thrombotic occasions has encouraged the swift enlargement of the to be had armamentarium to strive against pathologic thrombosis. Pathologic thrombosis performs a vital function within the pathogenesis of acute coronary syndromes (ACS), ischemic problems of percutaneous coronary intervention (PCI), venous thromboembolic ailment, and embolic issues of arrhythmias and numerous cardiomyopathies. Written by way of specialists within the box, Antithrombotic Drug remedy in Cardiovascular Disease conscientiously examines person and diverse mixtures of the on hand antithrombotic regimens together with fibrinolytic brokers, antiplatelet cures (aspirin, thieneopyridines, glycoprotein IIb/IIIa inhibitors), and anticogulant treatments (unfractionated heparin, low-molecular-weight heparins, direct thrombin inhibitors, and artificial issue X inhibitors), non-ST-segment elevation (NSTE) ACS and ST-segment elevation myocardial infarction (STEMI). an in depth evaluate, Antithrombotic Drug treatment in Cardiovascular Disease offers the facts demonstrating the efficacy of accessible antithrombotic remedies in particular affliction states equivalent to atrial traumatic inflammation, cardiomyopathy, valvular center disorder, and heparin-induced thrombocytopenia (HIT).
Read Online or Download Antithrombotic Drug Therapy in Cardiovascular Disease PDF
Best diseases books
A few persistent breathing illnesses together with power bronchitis, bronchial asthma, cystic fibrosis and bronchiectasis are characterised by means of mucus hypersecretion. Following harm to the airway epithelium, a fix strategy of dedifferentiation, regenerative proliferation and redifferentiation occurs that's consistently observed through mucus hypersecretion as a key point within the host defence mechanism.
This memoir of a committed health practitioner struggling with the AIDS epidemic in Haiti does greater than chronicle the tale of a terrible illness. it's a relocating tribute to the ample braveness, resilience, and dignity of a humans beset by means of tragedy. The Zombie Curse A Doctorâ€™s 25-Year trip into the center of the AIDS Epidemic in Haiti Arthur M.
This crucial reference deals a accomplished assessment of the graft-versus-leukemia (GVL) or -tumor (GVT) impression following allogeneic stem telephone transplantation and lymphocyte transfusion, protecting quite a lot of issues from alloimmune responses to medical functions of GVL, and supplying the fundamentals to appreciate the mechanisms of the GVL impact whereas demonstrating tools that use the GVL impact to remedy a better variety of melanoma sufferers.
- The Principal Diseases of Lower Vertebrates
- First Principles of Gastroenterology : The Basis of Disease and an Approach to Management 5th ed
- Diseases of the Nose, Throat and Ear. For Practitioners and Students
- Healthful eating as lifestyle (HEAL): integrative prevention for non-communicable diseases
Additional info for Antithrombotic Drug Therapy in Cardiovascular Disease
Mann KG, van’t Veer C, Cawthern K, Butenas S (1998) The role of the tissue factor pathway in initiation of coagulation. Blood Coagul Fibrinolysis 9:S3–S7 36. Fleck RA, Rao LVM, Rapaport SI, Varki N (1990) Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody. Thromb Res 57:765–781 37. Osterud B (1998) Tissue factor expression by monocytes: regulation and pathophysiological roles. Blood Coagul Fibrinolysis 9(Suppl 1):9–14 38.
Vasc Med 1:275–280 107. Rees DC, Cox M, Clegg JB (1995) World distribution of factor V Leiden. Lancet 345:1133–1134 108. Bertina RM (1997) Factor V Leiden and other coagulation risk factor mutations affecting thrombotic risk. Clin Chem 43:1678–1683 Antithrombotic Drug Therapy in Cardiology: The Role of Coagulation in Arterial and Venous Thrombosis 37 109. Segers K, Dahlback B, Nicolaes GA (2007) Coagulation factor V and thrombophilia: Background and mechanisms. Thromb Haemost 98:530–542 110. Bertina RM (1999) Molecular risk factors for thrombosis.
Despite single case reports, prospective studies have not shown an association between deficiency of antithrombin, protein C, or protein S and MI (142). Antithrombotic Drug Therapy in Cardiology: The Role of Coagulation in Arterial and Venous Thrombosis 33 SUMMARY The coagulation proteins have a vital role in the hemostatic process, defending the body from exsanguination during trauma. However, it is clear that dysregulation of the coagulation system can variously lead to venous thrombosis and contribute to the development of arterial atherothrombotic disease.
Antithrombotic Drug Therapy in Cardiovascular Disease by Edward F. Plow PHD, Peter Kelly MD (auth.), Arman T. Askari, A. Michael Lincoff (eds.)