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By Bhanu P. Chowdhary

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A. Fries Lehrstuhl für Tierzucht der Technischen Universität München, München (Germany) Abstract. We report the cloning and initial characterization of the genes encoding DGAT2 (diacylglycerol transferase 2), MOGAT1 and MOGAT2 (monoacylglycerol transferases 1 and 2) in domestic cattle (Bos taurus). The three closely related genes belong to a gene family with at least eight members in mammals and are candidate genes for quantitative traits related to dietary fat uptake, lipid synthesis and storage.

Frengen E, Weichenhan D, Zhao B, Osoegawa K, van Geel M, de Jong PJ: A modular positive selection bacterial artificial chromosome vector with multiple cloning sites. Genomics 58:250–253 (1999). Han CS, Sutherland RD, Jewett PB, Campbell ML, Meincke LJ, Tesmer JG, Mundt MO, Fawcett JJ, Kim U-J, Deaven LL, Doggett NA: Construction of a BAC contig map of chromosome 16q by twodimensional overgo hybridization. Genome Res 10:714–721 (2000). 38 Kappes SM, Keele JW, Stone RT, McGraw RA, Sonstegard TS, Smith TP, Lopes-Corrales NL, Beattie CW: A second-generation linkage map of the bovine genome.

Arthrogryposis is a complex of symptoms characterized by limbs congenital contractures having different origin. , 1997; Pozzatti, 2002). , 2003). , 1995). , 1998a). In this study, we comparatively FISH-map SMN in cattle, river buffalo, sheep and goat by refining its position in cattle and assigning, for the first time, this important gene to sheep, goat and river buffalo chromosomes. Furthermore, a comparative fiber-FISH on extended chromatin of both normal cattle and Piedmont calf affected by arthrogryposis revealed a possible duplication of the SMN gene in the latter.

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Animal genomics, Volume 102 by Bhanu P. Chowdhary


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